Search results for "Hemoglobin Saturation"
showing 4 items of 4 documents
Multimodal Device for Real-Time Monitoring of Skin Oxygen Saturation and Microcirculation Function
2019
The present study introduces a recently developed compact hybrid device for real-time monitoring of skin oxygen saturation and temperature distribution. The prototype involves a snapshot hyperspectral camera, multi-wavelength illuminator, thermal camera, and built-in computer with custom-developed software. To validate this device in-vivo we performed upper arm vascular occlusion on eight healthy volunteers. Palm skin oxygen saturation maps were analyzed in real-time using k-means segmentation algorithm and two-layer optical diffuse model. The prototype system demonstrated a satisfying performance of skin hyperspectral measurements in the spectral range of 507&ndash
Respiratory gas exchange in the rat spleen in situ and intrasplenic oxyhemoglobin saturation.
1979
Measurements of splenic respiratory gas exchange and of HbO2 saturations in the red pulp of the rat spleen have shown that there are no indications of a reduced intrasplenic O2 availability during normoxia. The present studies provide evidence that, in the normal spleen, the intrasplenic sequestration of red blood cells cannot be explained by an O2 deficiency in the red pulp since the commonly accepted notion of an intrasplenic hypoxia is not true.
Oxygenation of malignant tumors after localized microwave hyperthermia
1982
The oxyhemoglobin saturation (HbO2) of single red blood cells within tumor microvessels (diameter: 3-12 micrometers) of DS-Carcinosarcoma was studied using a cryophotometric micromethod. In untreated control tumors (mean tissue temperature approx. 35 degrees C) the measured values scattered over the whole saturation range from zero to 100 sat. %, the mean being 51 sat. %. Upon heating at 40 degrees C for 30 min, the oxygenation of the tumor tissue significantly improved as compared with control conditions. After 40 degrees C-hyperthermia a mean oxyhemoglobin saturation of 66 sat. % was obtained. In contradistinction to this, after 43 degrees C-hyperthermia the tumor oxygenation was signific…
Impact of Various Thermal Doses on the Oxygenation and Blood Flow in Malignant Tumors Upon Localized Hyperthermia
1984
Hyperthermia exhibits various direct cytocidal effects (Dickson, 1977; Overgaard, 1977; Suit, 1977). During heat treatment in vivo, several indirect mechanisms enhance the direct cell-killing capacity of hyperthermia. Therefore, the effective use of hyperthermia can overcome some of the well-known problems involved in modern radiation therapy at least in some malignant tumors.